The life journey of Patrick Hardison from Mississippi is truly extraordinary. He became the first American to receive a full face transplant in 2015, after a devastating house fire left his face and neck severely disfigured.

Before tragedy struck, Patrick was living a normal and fulfilling life. In 2001, as a volunteer firefighter, he responded to an emergency call without hesitation. But while inside the burning home, the structure suddenly collapsed, trapping him beneath the flames. Unable to escape, he suffered horrific burns to his upper body and face.

“My mask was melting onto my skin, and my hose had already melted,” Patrick later recalled.

First responder and close friend Jimmy Neal described the scene as unimaginable, telling CBS News that he had never seen anyone with such severe burns survive.

Patrick sustained third-degree burns to his face and scalp, along with serious injuries to his head, neck, and upper torso. The fire destroyed his ears, lips, most of his nose, and much of his eyelids.

For months, Patrick couldn’t even bring himself to look in the mirror. When he finally did, the shock was overwhelming. Doctors had used skin grafts to cover the damaged areas, leaving only a small opening so he could see.

“I thought, ‘This is it. I can’t live like this,’” he shared in an interview.

Over the years, Patrick endured more than 70 surgeries. He couldn’t fully close his eyes, and although doctors created skin flaps to protect his vision, the threat of blindness remained. Eating was painful, and everyday tasks became exhausting.

Public reactions were often cruel and hurtful. Strangers stared, children screamed, and Patrick struggled to be around people — even his own family at times. To protect himself, he wore sunglasses, a baseball cap, and ear prosthetics whenever he went out.

“There was no break from it,” he said. “Every time you stepped outside, you had to be ready for people’s reactions.”

As time passed, Patrick began to lose hope of ever living a normal life again. Then he heard about a woman in France who had received the world’s first partial face transplant after being attacked by her dog. For the first time in years, Patrick felt a spark of hope.

He later met Dr. Eduardo D. Rodriguez at NYU Langone Medical Center, who told him a transplant might be possible if a suitable donor could be found. After a long wait, a match was finally identified by LiveOnNY, an organization that coordinates organ donations in New York.

The donor was 26-year-old David Rodebaugh, who had suffered fatal brain injuries in a cycling accident. His mother, Nancy Millar, chose to donate her son’s organs — including his face — believing that part of David could live on by helping others.

She later said she saw something of her son in Patrick, especially knowing that Patrick had risked his own life as a firefighter.

The transplant surgery took 26 hours and required a team of nearly 100 medical specialists. Patrick was told his chances of survival were only 50 percent.

Against the odds, the operation was a success. He received a new face, scalp, ears, ear canals, and eyelids — allowing him to blink naturally again and protecting his eyesight.

“Everything in life involves risk,” Patrick later said. “When it’s your time, it’s your time — whether you’re walking down the street or lying in an operating room.”